Glycosyl compounds
Apexbio Technology LLC Bafilomycin D 98813-13-9 5mg
Bafilomycin D is an inhibitor targeting vacuolar-type H -ATPases (V-ATPases) displaying approximate IC of 2 nM in assays utilizing Neurospora crassa-derived enzymes V-ATPases function as proton pumps actively transporting protons across cellular membranes through ATP hydrolysis thus controlling pH homeostasis within intracellular compartments By selectively disrupting proton gradient formation mediated by V-ATPases Bafilomycin D serves as a useful investigative tool in studies of intracellular vesicular trafficking lysosome acidification endocytosis and related membrane transportation mechanisms in biomedical research contexts
Medchemexpress LLC LRRC32 beta 50ug | 50ug
LRRC32 is a key regulator of TGF- activation and maintains TGFB1 TGFB2 and TGFB3 in the latent state during extracellular storage by binding to latency-associated peptide (LAP) LRRC32 competes with LTBP1 for LAP binding and effectively regulates integrin-dependent TGF- activation GARP Latent TGF beta Complex Protein Human (Biotinylated HEK293 His-Avi) is a recombinant protein dimer complex containing human-derived GARP Latent TGF beta Complex protein expressed by HEK293 with C-Avi C-His labeled tag GARP Latent TGF beta Complex Protein Human (Biotinylated HEK293 His-Avi) has molecular weight of (73-78) kDa (GARP) 13 kDa (42-45) kDa (Latent TGF beta 1) respectively
Medchemexpress LLC Cathepsin D Human 100ug | 100ug
Cathepsin D protein is an acidic protease that actively participates in intracellular protein breakdown Studies have shown that it is critical in the processing of amyloid precursor protein (APP) with ADAM30-mediated cleavage and activation leading to APP degradation Cathepsin D Protein Human (HEK293 C-His) is the recombinant human-derived Cathepsin D protein expressed by HEK293 with C-6 His labeled tag
Medchemexpress LLC SIRP beta Mouse HE 50ug | 50ug
SIRP-beta (Sirpb CD172b) is a member of the signal-regulatory-protein (SIRP) family and also belongs to the immunoglobulin superfamily SIRP family members are receptor-type transmembrane glycoproteins Sirpb was found to interact with TYROBP/DAP12 a transmembrane adaptor protein bearing immunoreceptor tyrosine-based activation motifs resulting in the tyrosine phosphorylation of DAP12 and the subsequent recruitment of Syk to the Sirpb-DAP12 complex Sirpb is also implicated as a positive regulator of hematopoietic cells SIRP beta Protein Mouse (HEK293 His) is the recombinant mouse-derived SIRP beta protein expressed by HEK293 with C-His labeled tag